AQA · Biology · 8461
GCSE Biology: Producing monoclonal antibodies
Infection and response · AQA GCSE Biology (8461), specification point 4.3.2.1. Cards are generated from the exam board's own specification for "Producing monoclonal antibodies", and every card links back to the page it came from. Higher tier only. Separate science only. Specification © AQA — used with attribution.
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Monoclonal antibodies are produced from what?
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A single clone of cells.
Why can monoclonal antibodies target a specific chemical or cell?
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Each is specific to one binding site on one protein antigen.
Which animal's lymphocytes are used to produce monoclonal antibodies?
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Mouse lymphocytes.
What is a hybridoma cell?
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A cell formed by combining a mouse lymphocyte with a tumour cell.
What is the first step in producing monoclonal antibodies?
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Stimulating mouse lymphocytes to make a particular antibody.
Why are single hybridoma cells cloned?
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To produce many identical cells that all make the same antibody.
What is the final step in producing monoclonal antibodies?
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A large amount of the antibody is collected and purified.
Which two things can a hybridoma cell do?
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Divide and make the antibody.
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